Spectral and Electro¬migration Characteristics of Imidazole Ribosides

  • P. Vyskočilová Department of Analytical Chemistry, Faculty of Natural Science, Palacký University, Olomouc, Czech Republic
  • P. Hornik Department of Analytical Chemistry, Faculty of Natural Science, Palacký University, Olomouc, Czech Republic
  • D. Friedecký Laboratory of Inherited Metabolic Disorders, Department of Clinical Biochemistry, University Hospital, Olomouc, Czech Republic,
  • T. Adam Laboratory of Inherited Metabolic Disorders, Department of Clinical Biochemistry, University Hospital, Olomouc, Czech Republic,

Abstrakt

Some imidazole ribosides were synthesized, purified by ion exchange chromatography and analyzed by capillary micellar electrophoretic chromatography and zone electrophoresis. Basic spectral and electromigration characteristics of the ribosides at various pH are reported. The data on ribosides can be used in diagnosis of the known and as yet undescribed enzyme defects in the de novo purine synthesis.
Publikované
2007-04-15
Sekce
Články