Determination of Nanomolar Concentrations of Anthracyclines by Capillary Electrophoresis with UV Detection

  • A. Gavenda Department of Analytical Chemistry, Faculty of Science, Palacky University,
  • J. Sevcik Center of Analytical Chemistry of Molecular Structures, Faculty of Medicine, Palacky University,
  • J. Psotova Institute of Medical Chemistry, Faculty of Medicine, Palacky University, Olomouc

Abstrakt

On-line preconcentration was used to get better UV detection limits in capillary electrophoresis. The sweeping effect in micellar electrokinetic chromatography was used to detect trace amounts of the biologically active group of anthracyclines in model samples. The improved sweeping preconcentration technique provides for excellent detection limits decreasing down to concentration 10-9 mol.l-1.
Publikované
2000-12-15
Sekce
Články