Molecular Recognition with Novel Chromatographic Phases Based on Combination of Porphyrins and Expanded Porphyrins with Chiral Binaphthyl Derivatives: Application for the Separation of Biologically Important Substrates

  • I. Kavenova * * Department of Analytical Chemistry,** Department of Organic Chemistry, Institute of Chemical Technology, Prague; *** Department of Organic Chemistry and Biochemistry, University of Texas at Austin, Austin, Texas, USA
  • R. Holakovsky ** * Department of Analytical Chemistry,** Department of Organic Chemistry, Institute of Chemical Technology, Prague; *** Department of Organic Chemistry and Biochemistry, University of Texas at Austin, Austin, Texas, USA
  • M. Hovorka ** * Department of Analytical Chemistry,** Department of Organic Chemistry, Institute of Chemical Technology, Prague; *** Department of Organic Chemistry and Biochemistry, University of Texas at Austin, Austin, Texas, USA
  • V. Kriz * * Department of Analytical Chemistry,** Department of Organic Chemistry, Institute of Chemical Technology, Prague; *** Department of Organic Chemistry and Biochemistry, University of Texas at Austin, Austin, Texas, USA
  • P. Anzenbacher Jr. * * Department of Analytical Chemistry,** Department of Organic Chemistry, Institute of Chemical Technology, Prague; *** Department of Organic Chemistry and Biochemistry, University of Texas at Austin, Austin, Texas, USA
  • P. Matejka * * Department of Analytical Chemistry,** Department of Organic Chemistry, Institute of Chemical Technology, Prague; *** Department of Organic Chemistry and Biochemistry, University of Texas at Austin, Austin, Texas, USA
  • V. Kral * * Department of Analytical Chemistry,** Department of Organic Chemistry, Institute of Chemical Technology, Prague; *** Department of Organic Chemistry and Biochemistry, University of Texas at Austin, Austin, Texas, USA
  • J. W. Genge *** * Department of Analytical Chemistry,** Department of Organic Chemistry, Institute of Chemical Technology, Prague; *** Department of Organic Chemistry and Biochemistry, University of Texas at Austin, Austin, Texas, USA
  • J. L. Sessler *** * Department of Analytical Chemistry,** Department of Organic Chemistry, Institute of Chemical Technology, Prague; *** Department of Organic Chemistry and Biochemistry, University of Texas at Austin, Austin, Texas, USA

Abstrakt

A novel possibility for the chiral separation mode based on multiple recognition by mixed macrocycle-binaphthyl ligands on derivatized aminopropylsilica gel HPLC sorbents is presented. These novel chromatographic sorbents showed a great potential for aminoacid and saccharide separations.
Publikované
1998-03-15
Sekce
Články