Non-peptide Angiotensin II Receptor Antagonists - Potential Drugs against Hypertension

  • A. Lasiková * * Faculty of Chemical Technology, Slovak Technical University, Bratislava; ** Research Institute of Drugs, Modra, Slovak Republic
  • D. Vegh * * Faculty of Chemical Technology, Slovak Technical University, Bratislava; ** Research Institute of Drugs, Modra, Slovak Republic
  • V. Smahovsky ** * Faculty of Chemical Technology, Slovak Technical University, Bratislava; ** Research Institute of Drugs, Modra, Slovak Republic

Abstrakt

The review concerns the most effective structures of non-peptide Angiotensin II receptor antagonists as potential drugs for hypertension treatment. The structures are subdivided into three groups according to binding affinity to the receptor. The basic structure - activity relationships of these structures are discussed.
Publikované
1998-03-15
Sekce
Články