The Labelling of Monoclonal Antibody Anti-CD20 with Yttrium and Lutetium Radionuclides

  • F. Budský Institute of Nuclear Research Co., Řež
  • V. Miler Institute of Nuclear Research Co., Řež
  • Z. Málek Institute of Nuclear Research Co., Řež

Abstrakt

This contribution presents a method of conjugation of monoclonal antibody CD20 with diethylenetriaminepentaacetic anhydride, the preparation of yttrium-90 and lutetium-177 radionuclides and the preparation of complexes of the antibody with the radionuclides. The complexes show high specific activities.
Publikované
2009-02-15
Sekce
Články