Kotranslační děje aneb první okamžiky života proteinu

  • M. H. Kolář Ústav fyzikální chemie, Vysoká škola chemicko-technologická v Praze, Praha
Klíčová slova: ribozom, ribozomální tunel, sbalování proteinů, antibiotika, translační uvěznění, zastavení ribozomu, kotranslační děje

Abstrakt

Proteins are biopolymers composed of amino acids. Proteins play a role almost in all processes in living organisms. In cells, proteins are synthesized on ribosomes in a process called translation, where amino acids are connected one at a time by a chemical bond according to a pre-defined scenario stored as the genetic information. Relative to their lifetime, proteins spend non-negligible time attached to the ribosome. This review focuses on phenomena that involve a nascent protein before it is released from the ribosome, i.e., in the first moments of their own synthesis, co-translationally. The text partly covers a lecture given by the author at the Summer School for High School Teachers and Students organized by UCT Prague in August 2021.

Publikované
2021-10-15
Jak citovat
[1]
Kolář, M. 2021. Kotranslační děje aneb první okamžiky života proteinu. Chemické listy. 115, 10 (říj. 2021), 550-553.
Sekce
Bulletin